Clostridium difficile toxins

Clostridium difficile toxins
C. difficile enterotoxin A (308 kD) is secreted, enters eukaryotic cell by receptor-mediated endocytosis and once in cytoplasm glucosylates small G-proteins of rho family thereby inactivating them and leading to loss of actin filament bundles. Cytotoxin B (270 kD) is similar.

Dictionary of molecular biology. 2004.

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  • Clostridium difficile toxin A — is a toxin generated by Clostridium difficile.[1] It is similar to Clostridium difficile Toxin B. It is usually described as a enterotoxin,[2] but it also has some activity as a cytotoxin.[3] References …   Wikipedia

  • Clostridium difficile toxin B — cytotoxin Structure of C. difficile glucosyl transferase Toxin B showing UDP and glusose from PDB entry 2BVM [1] Identifiers …   Wikipedia

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  • Clostridium — SEM micrograph of Clostridium difficile colonies from a stool sample. Scientific classification Domain …   Wikipedia

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  • Clostridium — A group of anaerobic bacteria (bacteria that thrive in the absence of oxygen). There are 100+ species of Clostridium. They include, for examples, Clostridium difficile, Clostridium perfringens (also called Clostridium welchii), and Clostridium… …   Medical dictionary

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